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Aib

1-Aminoisobutyric acid (H2N-(Me)2C-COOH) or alpha-methyl-alanine.

Aib is an alpha amino acid that occurs in peptidic antibiotics (for example alamethicin) produced by microbial organisms. It is not one of the proteinogenic amino acids and rather rare in nature.

Aib is a strong helix inducer in peptides. Oligomers of Aib form 3-10 helices.

01-04-2007 01:16:19
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