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Amide hydrolysis

Amide hydrolysis involves the C-N bond being broken in reaction with water (hydrolysis). The reaction is catalysed by either acid or alkali.

image:amide_hydrolysis.png

Procedure:

The amide is heated under reflux with moderately concentrated acqueous acid or alkali. If an acid is used, the product contains Ammonium ions. If a alkali is used, the carboxylic acid loses an H+ ion and the product contains carboxylate ions.

01-04-2007 01:16:19
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