Aulus Cornelius Celsus (25 BC-50) was a Roman encyclopedist and possibly a doctor. His only extant work, the de Medicina , is the only surviving section of a much larger encyclopedia, and is a primary source on diet, pharmacy and surgery and related fields.
Celsus is credited with recording the cardinal signs of inflammation: calor (warmth), dolor (pain), tumor (swelling) and rubor (redness and hyperaemia). He also describes the preparation of opioids.
Celsus' work was rediscovered by Pope Nicholas V and published in 1478.
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