In Greek mythology, four people had the name Creusa.
- According to Pindar's 9th Pythian Ode, Creusa was a naiad and daughter of Gaia who bore Hypseus, King of the Lapiths to the river god Peneus. Hypseus had one daughter, Cyrene. When a lion attacked her father's sheep, Cyrene wrestled with the lion. Apollo happened along and immediately fell in love with her and kidnapped her. He took her to North Africa and founded the city of Cyrene in her name. The region, Cyrenaica, is also named for her. Together, she and Apollo had one son: Aristaeus.
- Daughter of King Creon of Corinth, Greece. After Jason divorced Medea, he married Creusa. Medea got even by giving Creusa a cursed dress that stuck to her body and burned her to death as soon as she put it on.
- Daughter of Priam, wife of Aeneas, mother of Ascanius. In Virgil's Aeneid she died escaping from Troy during the sack of Troy by the Greeks.
- Daughter of Erechtheus, mother of a son Achaeus, a daughter named Diomede, and presumably another son Ion according to Hesiod's Ehoeae but according to Euripides' Ion she was mother of Ion by Apollo and of Achaeus and Dorus by her husband Xuthus.