The Polish name Jan (John) was particularily popular among the szlachta family of Sapieha . It might refer to the following notable members of that clan:
- Jan Fryderyk Sapieha (1680–1751), Grand Recorder of Lithuania between 1706 and 1709, since 1716 the castellan of Troki and after 1735 the Grand Chancellor of Lithuania
- Jan Kazimierz Sapieha the Elder (?–1730), Grand Hetman of Lithuania
- Jan Paweł Sapieha (1609–1665), father of Jan Kazimierz the Younger, voivod of Wilno and (since 1656) the Grand Hetman of Lithuania.
- Jan Kazimierz Sapieha the Younger , (ca. 1642–1720), since 1700 held the title of a Duke. Since 1681 Field Hetman of Lithuania, the following year he also became the voivod of Wilno. In 1682 promoted to Grand Hetman of Lithuania.