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Piroxicam


Piroxicam

4-hydroxy-2-methyl-N-pyridin-2-yl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

Empirical formula C15H13N3O4S
Molecular weight 331.35
Bioavailability (Oral) unknown
Metabolism 4-10% renal
Half life 57 hours
Excretion 4-10% renal
Pregnancy category unknown

Piroxicam is a nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis, primary dysmenorrhoea, pyrexia; and as an analgesic, especially where there is an inflammatory component.

Mechanism of action

Piroxicam is an NSAID and, as such, is a non-selective cyclooxygenase (COX) inhibitor

Main article: Non-steroidal anti-inflammatory drug

Adverse effects

Piroxicam use can result in gastrointestinal toxicity, innitus, headache, and rash. The risk of adverse side efects is nearly ten times higher than with other NSAIDs.

Main article: Non-steroidal anti-inflammatory drug

01-04-2007 01:16:19
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