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San Pedro (cactus))
Description
San Pedro cactus (Trichocereus pachanoi) is a fast-growing columnar cactus native to the Andes of Peru, Ecuador and Bolivia. The plant is light to dark green, sometimes glaucous, and having 4-8 (usually 5-7) ribs. Groups of 1-4 small, yellow to light brown, spines are located at the nodes which are spaced evenly (approximately 2cm apart) along the ribs. San Pedro can grow up to 5 meters tall and have multiple branches, usually extending from the base.
Chemistry
San Pedro contains a number of psychoactive alkaloids, including the well-studied chemical mescaline (0.11 - 2.3%), and also 3,4-dimethoxyphenethylamine, 4-hydroxy-3-methoxyphenethylamine, 3-hydroxy-4,5-dimethoxyphenethylamine, 4-hydroxy-3,5-dimethoxyphenethylamine, anhalonidine, anhalinine, hordenine, tyramine, and 3-methoxytyramine.
Mescaline (3,4,5 - trimethoxy-ß-phenethylamine) is an hallucinogen (or entheogen) and stimulant which is also found in some other species of genus Trichocereus (i.e. Trichocereus bridgesii , Trichocereus peruvianus, and Trichocereus scopulicolus ") and the species Lophophora williamsii (peyote).
Anecdotal evidence suggests that the highest concentrations of active substances are found in the layer of green photosynthetic tissue just beneath the skin.
There are various techniques, simple and complex, by which material containing a much higher concentration of mescaline can be extracted from the cactus, and it is probably the most common source of mescaline.
Cultivation
San Pedro is very easy to grow in most areas. Because it grows naturally in the high altitude, high rainfall areas of the Andes, it can withstand temperatures far below that of many other cacti, however it does not tolerate. In fact its cultivation requirements are really more like 'normal' plants than most other cacti. San Pedro requires fertile, free-draining soil. They are susceptible to fungal diseases if overwatered, but are not nearly as sensitive as many other cacti, especially in warm weather. They can be sunburned and display a yellowing chlorotic reaction to overexposure to sunlight. In warm areas it is best to keep them out of direct sun in mid-summer.
In winter plants will etiolate , or become thin, due to lower levels of light. This may be problematic if the etiolated zone is not sufficiently strong to support future growth as the cactus may break in strong winds. Some people also find it visually undesirable. If you wish to avoid etiolation when temperatures drop and growth rates slow, encourage your San Pedro to enter winter dormancy by withholding water and fertiliser from it over the winter.
Cultivation from Seed
Trichocereus pachanoi seeds are quite easy to germinate and grow. Their main requirements consist of high humidity levels, free-draining soil mix, and enough (but not too much) water, light, and nutrition. There are a number of commonly used methods that satisfy these requirements and the choice of a particular method depends mainly on the scale of the cultivation operation.
Here is one method:
For soil, use coarse sharp sand (sieved river sand). Some people also find coco coir/peat, or mixtures, to be effective. The soil can be sterilised by cooking it in an oven on high for 1-2 hours. Sterilisation will be most effective if the sand is moist. If one is available, an autoclave would also be useful at this point. Some people find sterilisation to be unnecessary. This may depend on other factors. The soil is placed into trays (which can be sanitised with bleach beforehand if desired) and the seeds planted into it (when the soil has cooled). The seeds should be only just below the surface (ie two or three sand grains over them). The trays now need to be kept in a humid environment. This may be achieved by the use of ziplock bags, glass plates, or greenhouses, depending on scale. Seeds usually germinate within two weeks two a month, but sometimes come up after several months.
The seedlings stay in the humid environment for several months. During this time they must be continually checked for water and nutrient requirements, and fungal pathogens. Ensure the soil stays moist, but not overly wet. Nutrients can be provided with a liquid fertiliser at 1/8th strength whenever growth rate slows down. Fungi can be killed with a sulfur or copper-based fungicide. There have been some reports of seedlings responding negatively to these treatments so be very cautious with the amount you use. There is some evidence that garlic is also an effective fungicide.
If germinating your seeds in cold weather, a heat mat and flourescent light can be used. These should be set on a timer to mimic normal diurnal temperature cycles for germination but can be left on permanently for faster growth once all the seeds have sprouted. One good method for growing cacti seedlings using this setup is to germinate them in late winter and have them ready to go outside by spring as temperatures and light levels are increasing.
Traditional use
Legality
In most countries it is legal to cultivate San Pedro, but in countries where possession of mescaline and related compounds is illegal, cultivation for the purposes of consumption may be illegal. This is the case in the USA, Australia, Canada, and the UK, where it is currently legal to cultivate San Pedro unless it is for the purposes of consumption. It is unclear exactly how intent to consume would be proved. Possession of books, literature, and internet histories as well as large amounts of cactus (growing or not) may be enough evidence. The possession of material such as dried cactus flesh would probably be illegal in most countries where mescaline is scheduled, however fresh cactus material could be used (and is often) in normal cultivation activities, and so may not be proof of intent to consume.
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